COMPUTATIONAL POLYPHARMACOLOGY - A NEW STAGE OF DRUG DISCOVERY

orginal language: Uzbek

Authors

  • Fotima Adilova , ,
  • Nodirali Normakhamatov , ,
  • Rifkat Davronov , ,

Keywords:

multi-targeting ligands, drug repurposing, computer-aided drug design, in silico prediction, drug polypharmacology

Abstract

In recent years, the cost of drug design has risen sharply along with a high rate of failed clinical trials. To solve this problem, an alternative approach known as polypharmacology is used, which is designed to study the interaction of small molecules with multiple targets. This article presents computational methods to developing more effective drugs, because this approach allows to study the off-target activities and facilitates drug repositioning in the pharmaceutical industry

References

adabiyotlar ro'yxati

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Published

02.02.2022

How to Cite

COMPUTATIONAL POLYPHARMACOLOGY - A NEW STAGE OF DRUG DISCOVERY: orginal language: Uzbek. (2022). Problems and Perspectives of Pharmaceutics and Drug Discovery, 1(1), 20-26. https://pharmi-ojs.myprojects.uz/pppndd/article/view/11

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