COMPUTATIONAL POLYPHARMACOLOGY - A NEW STAGE OF DRUG DISCOVERY
orginal language: Uzbek
Keywords:
multi-targeting ligands, drug repurposing, computer-aided drug design, in silico prediction, drug polypharmacologyAbstract
In recent years, the cost of drug design has risen sharply along with a high rate of failed clinical trials. To solve this problem, an alternative approach known as polypharmacology is used, which is designed to study the interaction of small molecules with multiple targets. This article presents computational methods to developing more effective drugs, because this approach allows to study the off-target activities and facilitates drug repositioning in the pharmaceutical industry
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adabiyotlar ro'yxati
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