STUDYING THE ACUTE TOXICITY OF A MULTICOMPONENT DRY EXTRACT BASED ON MILK THISTLE, CORN, PEPPERMINT: Orginal langulage: Uzbek

Nafisa Salimova; Bakhtiyor Imamaliev; Rano Sultanova

STUDYING THE ACUTE TOXICITY OF A MULTICOMPONENT DRY EXTRACT BASED ON MILK THISTLE, CORN, PEPPERMINT

Orginal langulage: Uzbek

Authors

Nafisa Salimova , ,
Bakhtiyor Imamaliev , ,
Rano Sultanova , ,

Keywords:

acute toxicity, white mouse, milk thistle seeds, corn, peppermint leaves, extract

Abstract

Today, liver diseases are common, and the lack of effective drugs for the treatment of liver pathologies makes this problem actual. Based on the foregoing, the acute toxicity of a multicomponent dry extract (milk thistle seeds, corn stigmas, peppermint leaves) developed by employees of the Tashkent Pharmaceutical Institute was studied.

The study of acute toxicity was carried out according to the standard method on white mice.

As a result, it was found that dry extract is highly harmless, since LD₅₀> 6000 mg/kg - the preparation belongs to the fifth class of toxicity (practically non-toxic).

Based on the data obtained, it can be concluded that the preparation is highly harmless.

Downloads

Published

02.02.2022

Issue

Vol. 1 No. 1 (2022): The International Journal of Problems and Perspectives of Pharmaceutics and Drug Discovery

Section

Pharmacology and clinical pharmacology. Microbiological and histological studies

License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

How to Cite

STUDYING THE ACUTE TOXICITY OF A MULTICOMPONENT DRY EXTRACT BASED ON MILK THISTLE, CORN, PEPPERMINT: Orginal langulage: Uzbek. (2022). Problems and Perspectives of Pharmaceutics and Drug Discovery, 1(1), 125-128. https://pharmi-ojs.myprojects.uz/pppndd/article/view/64

Download Citation